OPA1 Antibody - Cat. #: CSB-PA016340HA01HU

SKU: CSB-PA016340HA01HU

Size :50ul

Clone Number:

Aliases:Dynamin like 120 kDa protein antibody; Dynamin like 120 kDa protein; mitochondrial antibody; Dynamin-like 120 kDa protein; form S1 antibody; FLJ12460 antibody; Juvenile kjer type optic atrophy antibody; KIAA0567 antibody; KJER type antibody; Large GTP binding protein antibody; largeG antibody; MGM1 antibody; Mitochondrial dynamin like 120 kDa protein antibody; Mitochondrial dynamin like GTPase antibody; NPG antibody; NTG antibody; OAK antibody; OPA 1 antibody; opa1 antibody; OPA1 gene antibody; OPA1_HUMAN antibody; Optic atrophy 1 (autosomal dominant) antibody; OPTIC ATROPHY 1 antibody; Optic atrophy 1 gene protein antibody; Optic atrophy 1 homolog (human) antibody; Optic atrophy protein 1 antibody; Optic atrophy protein 1 homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60313

Immunogen:Recombinant Human Dynamin-like 120 kDa protein, mitochondrial protein (183-418AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background:Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. May also play a role in mitochondrial genome maintenance.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OPA1

Research Areas:Neuroscience; Cardiovascular; Metabolism