OMA1 Antibody, Biotin conjugated - Cat. #: CSB-PA856923LD01HU

SKU: CSB-PA856923LD01HU

Size :50ug

Clone Number:

Aliases:2010001O09Rik antibody; DAB1 antibody; FLJ33782 antibody; Metalloendopeptidase OMA1 antibody; Metalloendopeptidase OMA1; mitochondrial antibody; Metalloprotease-related protein 1 antibody; mitochondrial antibody; MPRP 1 antibody; MPRP-1 antibody; MPRP1 antibody; OMA1 antibody; OMA1 homolog zinc metallopeptidase antibody; OMA1 homolog; zinc metallopeptidase (S. cerevisiae) antibody; OMA1 zinc metallopeptidase antibody; OMA1 zinc metallopeptidase homolog antibody; OMA1_HUMAN antibody; Overlapping activity with M-AAA protease antibody; Overlapping with the m-AAA protease 1 homolog antibody; peptidase antibody; YKR087C antibody; Zinc metallopeptidase OMA1 antibody; ZMPOMA1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96E52

Immunogen:Recombinant Human Metalloendopeptidase OMA1, mitochondrial protein (22-194AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OMA1

Research Areas:Cell biology; Metabolism