OGCP Polyclonal Antibody

SKU: BT-AP06342

Size:100μL

Background:Inner membrane mitochondrial proteins are responsible for the transport of metabolites across the mitochondrial membrane. SLC25A11 (Solute carrier family 25 member 11), also known as Mitochondrial 2-oxoglutarate/malate carrier protein, is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family. As an oxoglutarate/malate carrier, SLC25A11 transports 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for dicarboxylic acids and malate. SLC25A11 also participates in other important metabolic processes, such as the oxoglutarate/isocitrate shuttle and the malate-aspartate shuttle, as well as in nitrogen metabolism and in gluconeogenesis from lactate. SLC25A11 contains 3 solcar repeats, which is typical of substrate carrier proteins involved in energy transfer.

Research_area:Tags & Cell Markers

Target_protein:SLC25A11

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:OGCP Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):34062

UniProt accession:Human: Q02978; Mouse: Q9CR62; Rat: P97700

Synonyms:SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11

GeneID:Human: 8402; Mouse: 67863; Rat: 64201