NTCP2 Rabbit Polyclonal Antibody

SKU: BT-AP11586

Size:100μL

Background:This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism| so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines| such as familial hypertriglyceridemia (FHTG).

Research_area:Cancer; Metabolism; Signal transduction

Target_protein:SLC10A2

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NTCP2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):38280

UniProt accession:Human: Q12908; Mouse: P70172; Rat: Q62633

Synonyms:NTCP2

GeneID:Human: 6555; Mouse: 20494; Rat: 29500