NS Antibody - Cat. #: CSB-PA356065LA01IIE

SKU: CSB-PA356065LA01IIE

Size :50ug

Clone Number:

Aliases:NS antibody; Non-structural protein 1 antibody; NS1 antibody; NS1A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Influenza A virus (strain A/Udorn/307/1972 H3N2)

UniProt ID:P03495

Immunogen:Recombinant Influenza A virus Non-structural protein 1 protein (152-237AA)

Raised in:Rabbit

Species Reactivity:Influenza A virus

Tested Applications:ELISA

Background:Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3\'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1. In turn, unprocessed 3\' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm. Cellular protein synthesis is thereby shut off very early after virus infection. Viral protein synthesis is not affected by the inhibition of the cellular 3\' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NS

Research Areas: