NR2E1 Antibody - Cat. #: CSB-PA820920ESR1HU

SKU: CSB-PA820920ESR1HU

Size :50ul

Clone Number:

Aliases:hTll antibody; NR2E1 / Tailless antibody; nr2e1 antibody; NR2E1_HUMAN antibody; Nuclear receptor subfamily 2 group E member 1 antibody; Nuclear receptor TLX antibody; Orphan nuclear receptor NR2E1 antibody; Protein tailless homolog antibody; Tailless homolog antibody; Tll antibody; TLX antibody; XTLL antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y466

Immunogen:Recombinant Human Nuclear receptor subfamily 2 group E member 1 protein (106-385AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5\\\'-AAGGTCA-3\\\' in which the 5\\\' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NR2E1

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction; Stem cells