NR2C1 Antibody - Cat. #: CSB-PA016051ESR1HU

SKU: CSB-PA016051ESR1HU

Size :50ul

Clone Number:

Aliases:NR2C1 antibody; TR2 antibody; Nuclear receptor subfamily 2 group C member 1 antibody; Orphan nuclear receptor TR2 antibody; Testicular receptor 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P13056

Immunogen:Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5\\\'-AGGTCA-3\\\' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NR2C1

Research Areas:Epigenetics and Nuclear Signaling