NOX4 Antibody, Biotin conjugated - Cat. #: CSB-PA015961LD01HU

SKU: CSB-PA015961LD01HU

Size :50ug

Clone Number:

Aliases:Kidney oxidase 1 antibody; Kidney oxidase-1 antibody; Kidney superoxide producing NADPH oxidase antibody; Kidney superoxide-producing NADPH oxidase antibody; KOX 1 antibody; KOX antibody; Kox-1 antibody; KOX1 antibody; NADPH antibody; NADPH oxidase 4 antibody; Nox4 antibody; NOX4_HUMAN antibody; Renal NAD(P)H oxidase antibody; Renal NAD(P)H-oxidase antibody; RENOX antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NPH5

Immunogen:Recombinant Human NADPH oxidase 4 protein (210-424AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NOX4

Research Areas:Cardiovascular; Cell biology; Metabolism; Signal transduction