NLRX1 antibody , Cat. # FNab05759

SKU: FNab05759

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).

Immunogen:NLR family member X1

Synonyms:Caterpiller protein 11.3, CLR11.3, DLNB26, NLR family member X1, NLRX1, NOD26, NOD5, NOD9

Observed MW:110 kDa

Uniprot ID:Q86UT6

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF, IHC, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

Gene ID:79671

Research Area:Immunology