NFKBIB Monoclonal Antibody

SKU: E-AB-22175

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: IκB β

Target Synonym: I kappa B beta;I-kappa-B-beta;IkappaBbeta;IKB beta;IkB-B;IkB-beta;IKBB;IKBB;IkBbeta;NF kappa BIB;NF-kappa-B inhibitor beta;NF-kappa-BIB;Nfkbib;Thyroid receptor interacting protein 9;Thyroid receptor-interacting protein 9;TR interacting protein 9;TR-interacting protein 9;TRIP-9;TRIP9

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human;Mouse;Rat

Application: IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: 3E4

UNIProt ID: Q15653

Accession:

Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Protein A purification

Dilution: IHC 1:100-200

Calculated MW:

ObservedMW: