NEFM Monoclonal Antibody

SKU: BT-MCA4685

Size:100μL

Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research_area:Neuroscience

Target_protein:NEFM

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2G12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NEFM

Immunogen:Purified recombinant fragment of human NEFM (AA: 381-443 ) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):102.4kDa

UniProt accession:P07197

Synonyms:NFM, NEF3, NF-M

GeneID:4741