NDE1 Antibody - Cat. #: CSB-PA889142DSR2HU

SKU: CSB-PA889142DSR2HU

Size :50ul

Clone Number:

Aliases:FLJ20101 antibody; HOM TES 87 antibody; LIS1 interacting protein NUDE1 rat homolog antibody; LIS1 interacting protein NUDE1 antibody; LIS4 antibody; NDE 1 antibody; NDE1 antibody; NDE1_HUMAN antibody; Nuclear distribution gene E homolog 1 antibody; Nuclear distribution protein nudE homolog 1 antibody; NUDE 1 antibody; NudE antibody; NudE nuclear distribution gene E homolog 1 (A. nidulans) antibody; NudE nuclear distribution gene E homolog 1 antibody; NUDE1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NXR1

Immunogen:Recombinant Human Nuclear distribution protein nudE homolog 1 protein (1-110AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NDE1

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cell biology