Nanog P8 rabbit pAb

SKU: ES2895

Size: 100μL

Source:Rabbit

Applications:WB;IF;ELISA;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200

Immunogen:The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):35kD

Human_gene_id:388112

Human_swiss_prot_no:Q6NSW7

Subcellular_location:Nucleus .

Other_name:NANOGP8; Putative homeobox protein NANOGP8

Background:This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],