MX1 Antibody - Cat. #: CSB-PA015249LA01HU

SKU: CSB-PA015249LA01HU

Size :50ug

Clone Number:

Aliases:Human interferon regulated resistance GTP binding protein MXA antibody; IFI 78 antibody; IFI 78K antibody; IFI-78K antibody; IFI78 antibody; IFI78K antibody; Interferon induced GTP binding protein Mx1 antibody; Interferon induced protein p78 antibody; Interferon inducible protein p78 antibody; Interferon regulated resistance GTP binding protein antibody; Interferon regulated resistance GTP binding protein MxA antibody; Interferon-induced GTP-binding protein Mx1 antibody; Interferon-induced protein p78 antibody; Interferon-regulated resistance GTP-binding protein MxA antibody; MX 1 antibody; MX antibody; MX dynamin-like GTPase 1 antibody; MX1 antibody; MX1_HUMAN antibody; MxA antibody; Myxoma resistance protein 1 antibody; Myxovirus (influenza virus) resistance 1 interferon inducible antibody; Myxovirus (influenza virus) resistance 1 interferon inducible protein p78 antibody; Myxovirus (influenza) resistance 1 homolog of murine antibody; Myxovirus resistance 1; mouse; homolog of antibody; Myxovirus resistance protein 1 antibody; N-terminally processed antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20591

Immunogen:Recombinant Human Interferon-induced GTP-binding protein Mx1 protein (7-172AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000

Background:Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MX1

Research Areas:Immunology; Microbiology