MRPL40 Polyclonal Antibody

SKU: E-AB-19169

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MRPL40

Target Synonym: 39S ribosomal protein L40;39S ribosomal protein L40 mitochondrial;39S ribosomal protein L40;mitochondrial precursor;FLJ41774;L40mt;MGC9400;mitochondrial;Mitochondrial ribosomal protein L40;MRP 40;MRP L22;MRP-L40;MRP40;MRPL22;MRPL40;NLVCF;Nuclear localization signal containing protein deleted in velocardiofacial syndrome;Nuclear localization signal deleted in velocardiofacial syndrome;Nuclear localization signal-containing protein deleted in velocardiofacial syndrome;RM40;Up-regulated in metastasis;URIM

Research Areas: Epigenetics and Nuclear Signaling;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NQ50

Accession:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.

Concentration: 1.44 mg/mL

Immunogen: Fusion protein of human MRPL40

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:100-1:300

Calculated MW: 24 kDa

ObservedMW: Refer to figures