Mouse Wap Four-Disulfide Core Domain Protein 2, WFDC2 ELISA Kit

SKU: E2567Mo

Size:96 Tests-1 Kit

Background:WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 (HE4) - is a protein that in humans is encoded by the WFDC2 gene. HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers.[5] The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:WFDC2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:14.22ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:WAP four-disulfide core domain protein 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9DAU7

MASS(Da):18,032

GeneID:67701

Synonyms:1600023A02Rik;HE4;WA;WAP domain-containing protein HE4;WAP four-disulfide core domain protein 2;WAP5;WFDC2

Gene names:Wfdc2

Standard solution:9600ng/L