Mouse TrkB ELISA Kit PicoKine®

SKU: EK0849

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: NTRK2

Specificity: Natural and recombinant mouse TrkB

Background: TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene.[1] TrkB is the high affinity catalytic receptor for several neurotrophins, which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The TrkB receptor is part of the large family of receptor tyrosine kinases. A tyrosine kinase is an enzyme which is capable of adding a phosphate group to certain tyrosines on target proteins, or substrates.Soppet et al. [2] demonstrated that the gp145 gene product of the TRKB gene is rapidly phosphorylated on tyrosine residues upon exposure to BDNF and NTF3. The standard product used in this kit is recombinant TrkB, a 49.5KDa glycoprotein, C32—H439.

Immunogen: Expression system for standard: NS0; Immunogen sequence: C32-H429

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Reference:

Uniprot ID: P15209

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 18212

Protein Name: BDNF/NT-3 growth factors receptor

Gene Full Name: neurotrophic tyrosine kinase, receptor, type 2

Synonyms: GP145 TrkB; NTRK2; TrkB; TrkB tyrosine kinase