Mouse Transcription Factor Sox-2, SOX2 ELISA Kit

SKU: E2518Mo

Size:96 Tests-1 Kit

Background:Transcription factor that forms a trimeric complex with POU5F1 (OCT3/4) on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (PubMed: 15863505, PubMed: 17097055, PubMed: 19740739). Binds to the proximal enhancer region of NANOG (PubMed: 15863505). Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (PubMed: 22198669). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity).

Research_area:Neuroscience

Applications:ELISA

Target_protein:SOX2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.11ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor Sox-2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48432

MASS(Da):34,454

GeneID:20674

Synonyms:SOX 2;SOX2;Transcription factor SOX-2

Gene names:SOX2

Standard solution:4800ng/L