Mouse Transcription Factor Hes-1, HES1 ELISA Kit

SKU: E2588Mo

Size:96 Tests-1 Kit

Background:Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:HES1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.098ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor Hes-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35428

MASS(Da):29,749

GeneID:15205

Synonyms:Hairy and enhancer of split 1;HES 1;HES1;Transcription factor HES-1

Gene names:HES1

Standard solution:64ng/ml