Mouse Toll-like Receptor 5, TLR-5 ELISA Kit

SKU: E2515Mo

Size:96 Tests-1 Kit

Background:Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.

Research_area:Immunology

Applications:ELISA

Target_protein:TLR5

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:14.05ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Toll-Like Receptor 5

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JLF7

MASS(Da):97,627

GeneID:53791

Synonyms:TLR 5;TLR5;Toll-like receptor 5

Gene names:TLR5

Standard solution:9600ng/L