Mouse TNFsR I ELISA Kit PicoKine®

SKU: EK0529

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Tnfrsf1a

Specificity: Natural and recombinant mouse TNFR1

Background: Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane receptor that binds tumor necrosis factor-alpha (TNF alpha). The protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. And this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L30-A212

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Reference:

Uniprot ID: P25118

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 21937

Protein Name: Tumor necrosis factor receptor superfamily member 1A

Gene Full Name: tumor necrosis factor receptor superfamily, member 1a

Synonyms: CD120a; FPF; p55; p55 R; p60; TBP1; TBPI; TNF R; TNF R I; TNF R1; TNF R55; TNF Receptor 1; TNF Receptor I; TNF RI; TNFAR; TNFR I; TNFR1; TNFR55; TNFR60; TNFRSF1A