Mouse TNFSF18/GITRL ELISA Kit PicoKine®

SKU: EK1308

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: TNFSF18

Specificity: Natural and recombinant mouse TNFSF18

Background: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T47-S173

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Uniprot ID: Q7TS55

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 240873

Protein Name: Tumor necrosis factor ligand superfamily member 18

Gene Full Name: tumor necrosis factor (ligand) superfamily, member 18

Synonyms: AITRL; GITRL; hGITRL; TL6; TNFSF18