Mouse TIM-3/HAVCR2 ELISA Kit PicoKine®

SKU: EK1645

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Havcr2

Specificity: Natural and recombinant mouse TIM-3

Background: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in mouses is encoded by the HAVCR2 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Immunogen: Expression system for standard: NS0; Immunogen sequence: R20-A193

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: Q8VIM0

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 171285

Protein Name: Hepatitis A virus cellular receptor 2 homolog

Gene Full Name: hepatitis A virus cellular receptor 2

Synonyms: CD366; HAVcr 2; HAVCR2; KIM 3; T cell membrane protein 3; Tim 3; TIM3; TIM-3; TIMD 3; TIMD3