Mouse Protein O-Glucosyltransferase 1, POGLUT1 ELISA Kit

SKU: E0720Mo

Size:96 Tests-1 Kit

Background:Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed: 21949356, PubMed: 26496195). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed: 21949356, PubMed: 26496195). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (By similarity). Notch glucosylation does not affect Notch ligand binding (By similarity). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (PubMed: 26496195).

Research_area:Others

Applications:ELISA

Target_protein:POGLUT1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.151ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Protein O-Glucosyltransferase 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8BYB9

MASS(Da):46,379

GeneID:224143

Synonyms:CAP10-like 46 kDa protein;KTEL motif-containing protein 1;O-glucosyltransferase Rumi homolog;POGLUT 1;POGLUT1;Protein O-glucosyltransferase 1;Protein O-xylosyltransferase POGLUT1;Rumi;Wing-shaped neural plate protein;Wsnp

Gene names:POGLUT1

Standard solution:96ng/ml