Mouse Protein Hexim1, HEXIM1 ELISA Kit

SKU: E2389Mo

Size:96 Tests-1 Kit

Background:Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.

Research_area:Others

Applications:ELISA

Target_protein:HEXIM1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.63ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein HEXIM1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8R409

MASS(Da):40,243

GeneID:192231

Synonyms:Cardiac lineage protein 1;HEXIM 1;HEXIM1;Protein HEXIM1

Gene names:HEXIM1

Standard solution:960ng/L