Mouse Probable carboxypeptidase PM20D1,PM20D1 ELISA KIT

SKU: E2360Mo

Size:96 Tests-1 Kit

Background:Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction (PubMed:27374330, PubMed:29533650, PubMed:29967167, PubMed:32271712, PubMed:32402239) (Probable). Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure (PubMed:27374330, PubMed:29967167, PubMed:32271712). PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles (PubMed:32402239). {ECO:0000269|PubMed:27374330, ECO:0000269|PubMed:29533650, ECO:0000269|PubMed:29967167, ECO:0000269|PubMed:32271712, ECO:0000269|PubMed:32402239, ECO:0000305|PubMed:31659023}.

Research_area:

Applications:ELISA

Target_protein:Pm20d1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.025ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Probable carboxypeptidase PM20D1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8C165

MASS(Da):55663

GeneID:212933

Synonyms:Pm20d1

Gene names:Pm20d1

Standard solution:24ng/mL