Mouse Phenylalanine-4-hydroxylase, PAH ELISA Kit

SKU: E2339Mo

Size:96 Tests-1 Kit

Background:Phenylalanine hydroxylase (PAH) (EC 1.14.16.1) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH4, a pteridine cofactor) and a non-heme iron for catalysis. During the reaction, molecular oxygen is heterolytically cleaved with sequential incorporation of one oxygen atom into BH4 and phenylalanine substrate. In humans, mutations in its encoding gene, PAH, can lead to the metabolic disorder phenylketonuria.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PAH

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:7.92ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Phenylalanine-4-hydroxylase

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P16331

MASS(Da):51,900

GeneID:18478

Synonyms:AW106920;PAH;Phe-4-monooxygenase;Phenylalanine-4-hydroxylase

Gene names:Pah

Standard solution:3200ng/L