Mouse Neurogenic locus notch homolog protein 3,NOTCH3 ELISA KIT

SKU: E1394Mo

Size:96 Tests-1 Kit

Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May play a role during CNS development. {ECO:0000250|UniProtKB:Q9R172, ECO:0000250|UniProtKB:Q9UM47}.

Research_area:

Applications:ELISA

Target_protein:Notch3

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Neurogenic locus notch homolog protein 3

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q61982

MASS(Da):244248

GeneID:18131

Synonyms:Notch3

Gene names:Notch3

Standard solution:24ng/ml