GeneBio Systems
Mouse LIF ELISA Kit PicoKine®
Mouse LIF ELISA Kit PicoKine®
SKU:EK0580
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Size: 96 wells/kit, with removable strips.
Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Form:
Reactivity: Mouse
Applications: ELISA
Application Details:
Gene Name: Lif
Specificity: Natural and recombinant mouse LIF
Background: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.
Immunogen: Expression system for standard: E.coli; Immunogen sequence: S24-F203
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Reference:
Uniprot ID: P09056
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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
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Gene ID: 16878
Protein Name: Leukemia inhibitory factor
Gene Full Name: leukemia inhibitory factor
Synonyms: CDF; D factor; DIA; Emfilermin; HILDA; Leukemia inhibitory factor; LIF; Melanoma derived LPL inhibitor; MLPLI
