Mouse Leucine-rich Repeat-containing G-protein Coupled Receptor 5, LGR5 ELISA Kit

SKU: E2015Mo

Size:96 Tests-1 Kit

Background:Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:LGR5

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.93ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z1P4

MASS(Da):99,666

GeneID:14160

Synonyms:G-protein coupled receptor 49;Leucine-rich repeat-containing G-protein coupled receptor 5;LGR 5;LGR5;Orphan G-protein coupled receptor FEX

Gene names:LGR5

Standard solution:4800ng/L