Mouse latent transforming growth factor beta binding protein 1,LTBP1 ELISA KIT

SKU: E1193Mo

Size:96 Tests-1 Kit

Background:Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta. {ECO:0000250|UniProtKB:Q14766}.

Research_area:

Applications:ELISA

Target_protein:Ltbp1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:latent transforming growth factor beta binding protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8CG19

MASS(Da):186717

GeneID:268977

Synonyms:Ltbp1

Gene names:Ltbp1

Standard solution:24ng/ml