Mouse IL-21/Interleukin-21 ELISA Kit PicoKine®

SKU: EK0797

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: IL21

Specificity: Natural and recombinant mouse IL-21

Background: Interleukin-21 is a protein that in humans is encoded by the IL21 gene. Interleukin 21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. By radiation hybrid analysis, the IL21 gene is mapped to chromosome 4q26-q27, near the IL2 gene. IL21 stimulates B-cell proliferation in an anti-CD40-dependent manner but inhibits proliferation stimulated by IL4 plus anti-IgM. The biologic effects of IL21 on NK cells differ between species, with human IL21 enhancing NK cell proliferation and murine IL21 inhibiting NK cell proliferation. IL21 is a cytokine highly expressed by mouse T (H)17 cells.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: P25-S146

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Reference:

Uniprot ID: Q9ES17

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 60505

Protein Name: Interleukin-21

Gene Full Name: interleukin 21

Synonyms: IL 21; IL21; IL-21; interleukin 21; Za11