Mouse IL-12(p70) ELISA Kit PicoKine®

SKU: EK0422

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Il12a

Specificity: Natural and recombinant mouse IL-12(P70)

Background: Interleukin (IL)-12 is a 70-KDa cytokine comprised of two disulfide-linked proteins (p35 and p40) and is essential for the initiation of effective immune response. And the IL-12p70 is a heterodimer of p35 and p40 subunits; it is an important cytokine secreted by antigen-presenting cells in response to antigenic stimulation. Gene expression analysis of the IL-12 cytokine family subunits revealed that both strains induced high levels of p40 (protein chain communal to IL-12 p70 and IL-23) as well as p19, a subunit of IL-23. Conversely only ACT- 18HS19 infection induced consistent transcription of IL-12 p35, a subunit of IL-12 p70. The standard product used in this kit is recombinant mouse IL-12 p70 comprising of a 193 amino acids p35 chain and a 313 amino acids p40 chain connected by a disulfide bond.

Immunogen: Expression system for standard: NS0; Immunogen sequence: (M23-S335)+ (R23-A215)

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P43431

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 16159

Protein Name: Interleukin-12 subunit alpha

Gene Full Name: interleukin 12a

Synonyms: CLMF; CLMF p35; IL 12 subunit p35; IL 12A; IL-12; IL12 p70; IL-12 p70; IL12A; IL-12A; IL12p70; IL12-p70; Interleukin 12 subunit alpha; NFSK; NKSF1; P35