Mouse Gp130/IL6ST EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0577

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: IL6ST

Specificity: Natural and recombinant mouse Gp130

Background: GP130 (Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane protein which is the founding member of the class of all cytokine receptors. The GP130 gene is mapped on 5q11.2. Gp130 showed an apparent molecular mass of 130 kD by SDS-PAGE. Gp130 is involved in the formation of high-affinity IL6-binding sites and in IL6 signal transduction. Sgp130 has a role in modulating signals transduced by membrane-bound gp130. Gp130 is an important part of many different types of signaling complexes.Gp130 molecules with mutations in either of these segments could not transduce a growth signal.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q23-E617

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Reference:

Uniprot ID: Q00560

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 16195

Protein Name: Interleukin-6 receptor subunit beta

Gene Full Name: interleukin 6 signal transducer

Synonyms: CD130; CDw130; Glycoprotein 130; GP130; GP130 RAPS; IL 6 receptor subunit beta; IL 6R beta; IL 6R subunit beta; IL 6RB; IL6R beta; IL-6RB; IL6ST; IL-6ST; IL 6ST; Membrane glycoprotein 130