Mouse Fructose-bisphosphate Aldolase B, ALDOB ELISA Kit

SKU: E2080Mo

Size:96 Tests-1 Kit

Background:Aldolase B also known as fructose-bisphosphate aldolase B or liver-type aldolase is one of three isoenzymes (A, B, and C) of the class I fructose 1,6-bisphosphate aldolase enzyme (EC 4.1.2.13), and plays a key role in both glycolysis and gluconeogenesis. The generic fructose 1,6-bisphosphate aldolase enzyme catalyzes the reversible cleavage of fructose 1,6-bisphosphate (FBP) into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) as well as the reversible cleavage of fructose 1-phosphate (F1P) into glyceraldehyde and dihydroxyacetone phosphate. In mammals, aldolase B is preferentially expressed in the liver, while aldolase A is expressed in muscle and erythrocytes and aldolase C is expressed in the brain. Slight differences in isozyme structure result in different activities for the two substrate molecules: FBP and fructose 1-phosphate. Aldolase B exhibits no preference and thus catalyzes both reactions, while aldolases A and C prefer FBP.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ALDOB

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.155ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Fructose-bisphosphate aldolase B

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q91Y97

MASS(Da):39,507

GeneID:230163

Synonyms:Al;Ald;Aldo2;Aldo-2;ALDOB;Aldolase 2;BC016435;Fructose-bisphosphate aldolase B;Liver-type aldolase;

Gene names:Aldob

Standard solution:96ng/mL