Mouse Formin-binding protein 1,FNBP1 ELISA KIT

SKU: E1244Mo

Size:96 Tests-1 Kit

Background:Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May act as a link between RND2 signaling and regulation of the actin cytoskeleton. May be required for the lysosomal retention of FASLG/FASL (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:Fnbp1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:56.2pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Formin-binding protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q80TY0

MASS(Da):71344

GeneID:14269

Synonyms:Fnbp1 Fbp17 Kiaa0554

Gene names:Fnbp1

Standard solution:12800pg/ml