Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit

SKU: E1211Mo

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Research_area:Others

Applications:ELISA

Target_protein:DKK2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:7.35ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf Related Protein 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9QYZ8

MASS(Da):28,432

GeneID:56811

Synonyms:Dickkopf-2;Dickkopf-related protein 2;DKK 2;DKK2;Dkk-2;mDkk-2

Gene names:DKK2

Standard solution:3200ng/L