Mouse Coiled-coil Domain-containing Protein 134, CCDC134 ELISA Kit

SKU: E1950Mo

Size:96 Tests-1 Kit

Background:In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling. In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CCDC134

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.054ng/mL

Detection range:0.1-38ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Coiled-Coil Domain-Containing Protein 134

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8C7V8

MASS(Da):26,495

GeneID:76457

Synonyms:CCDC134;Coiled-coil domain-containing protein 134

Gene names:CCDC134

Standard solution:40ng/mL