Mouse Cluster of differentiation 19,CD19 ELISA KIT

SKU: E0097Mo

Size:96 Tests-1 Kit

Background:Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores (PubMed:9382888, PubMed:12387743, PubMed:20101619). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:7542548, PubMed:7543183, PubMed:9317126). Required for normal differentiation of B-1 cells (PubMed:7542548, PubMed:7543183, PubMed:12387743). Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:7542548, PubMed:9317126, PubMed:12387743). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:7542548, PubMed:7543183, PubMed:12387743). {ECO:0000250|UniProtKB:P15391, ECO:0000269|PubMed:12387743, ECO:0000269|PubMed:20101619, ECO:0000269|PubMed:7542548, ECO:0000269|PubMed:7543183, ECO:0000269|PubMed:9317126, ECO:0000269|PubMed:9382888}.

Research_area:

Applications:ELISA

Target_protein:Cd19

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cluster of differentiation 19

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P25918

MASS(Da):60149

GeneID:12478

Synonyms:Cd19

Gene names:Cd19

Standard solution:24ng/ml