Mouse CCR4-NOT transcription complex subunit 6,CNOT6 ELISA KIT

SKU: E2798Mo

Size:96 Tests-1 Kit

Background:Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors. Mediates cell proliferation and cell survival and prevents cellular senescence. {ECO:0000250|UniProtKB:Q9ULM6}.

Research_area:

Applications:ELISA

Target_protein:Cnot6

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.23ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8K3P5

MASS(Da):63304

GeneID:104625

Synonyms:Cnot6 Ccr4 Kiaa1194

Gene names:Cnot6

Standard solution:64ng/ml