Mouse Caveolin-1, CAV1 ELISA Kit

SKU: E1914Mo

Size:96 Tests-1 Kit

Background:May act as a scaffolding protein within caveolar membranes (By similarity). Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed: 19546242). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (PubMed: 10816572). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).

Research_area:Neuroscience

Applications:ELISA

Target_protein:CAV1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:23.57ng/L

Detection range:50-10000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Caveolin-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P49817

MASS(Da):20,539

GeneID:12389

Synonyms:CAV 1;CAV1;Caveolin-1

Gene names:CAV1

Standard solution:12800ng/L