Mouse Bone Morphogenetic Protein 10,BMP10 ELISA KIT

SKU: E0768Mo

Size:96 Tests-1 Kit

Background:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines (By similarity). {ECO:0000250|UniProtKB:O95393, ECO:0000269|PubMed:15073151, ECO:0000269|PubMed:15109497, ECO:0000269|PubMed:16798733}.

Research_area:

Applications:ELISA

Target_protein:Bmp10

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:8.25pg/ml

Detection range:18.75-1200pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein 10

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R229

MASS(Da):47888

GeneID:12154

Synonyms:Bmp10

Gene names:Bmp10

Standard solution:2400pg/ml