Mono-methyl-H2AFZ (K7) Antibody - Cat. #: CSB-PA010100OA07me1HU

SKU: CSB-PA010100OA07me1HU

Size :50ul

Clone Number:

Aliases:Histone H2A.Z (H2A/z), H2AFZ, H2AZ

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P0C0S5

Immunogen:Synthesized peptide derived from Human Histone H2A.Z protein (2-14aa)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100

Background:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:H2AFZ

Research Areas:Epigenetics and Nuclear Signaling