MMP7 (Cleaved-Tyr95) Rabbit Polyclonal Antibody

SKU: BT-AP03638

Size:100μL

Background:Catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I| II| IV| V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).|cofactor:Binds 2 calcium ions per subunit.|cofactor:Binds 2 zinc ions per subunit.|The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion| thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.|Degrades casein| gelatins of types I| III| IV| and V| and fibronectin. Activates procollagenase.|Belongs to the peptidase M10A family.|

Research_area:Cancer; Cardiovascular; Cell biology; Signal transduction

Target_protein:MMP7

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MMP7

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):29370

UniProt accession:Human: P09237; Mouse: Q10738; Rat: P50280

Synonyms:MMP7 ;Cleaved-Tyr95; Matrilysin; EC 3.4.24.23; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase

GeneID:Human: 4316; Mouse: 0; Rat: 25335