MMP14 Antibody - Cat. #: CSB-PA897896

SKU: CSB-PA897896

Size :100ul

Clone Number:

Aliases:Matrix metallopeptidase 14 (membrane inserted) antibody; Matrix metalloproteinase 14 antibody; Matrix metalloproteinase-14 antibody; Membrane type 1 matrix metalloproteinase antibody; Membrane type 1 metalloprotease antibody; Membrane type matrix metalloproteinase 1 antibody; Membrane-type matrix metalloproteinase 1 antibody; Membrane-type-1 matrix metalloproteinase antibody; MMP 14 antibody; MMP X1 antibody; MMP-14 antibody; MMP-X1 antibody; Mmp14 antibody; MMP14_HUMAN antibody; MMPX1 antibody; MT MMP 1 antibody; MT-MMP 1 antibody; MT1 MMP antibody; MT1-MMP antibody; MT1MMP antibody; MTMMP 1 antibody; MTMMP1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P50281

Immunogen:Synthesized peptide derived from Human MMP-14.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

Bimal K. Ray, Circ. Res., Nov 2004; 95: 1082 - 1090.
Sharon Elliot, Invest. Ophthalmol. Vis. Sci., Apr 2006; 47: 1696 - 1702.
Hongqing Q. Ye, Invest. Ophthalmol. Vis. Sci., Sep 2000; 41: 2894.
Leanne J. Bakke, Biol Reprod, Jun 2002; 66: 1627.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MMP14

Research Areas:Cancer?Cardiovascular?Cell biology;Metabolism;Signal transduction