MGME1 Antibody, FITC conjugated - Cat. #: CSB-PA880084LC01HU

SKU: CSB-PA880084LC01HU

Size :50ug

Clone Number:

Aliases:MGME1 antibody; C20orf72 antibody; DDK1Mitochondrial genome maintenance exonuclease 1 antibody; EC 3.1.-.- antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BQP7

Immunogen:Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MGME1

Research Areas:Others