MEK1 antibody , Cat. # FNab05112

SKU: FNab05112

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:MEK1 is also named as MAP2K1(mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated.

Immunogen:mitogen-activated protein kinase kinase 1

Synonyms:ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, MEK1, MKK1, PRKMK1

Observed MW:40 kDa

Uniprot ID:Q02750

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200

Gene ID:5604

Research Area:Immunology, Signal Transduction, Metabolism