MDSP Rabbit Polyclonal Antibody

SKU: BT-AP11279

Size:100μL

Background:Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family| the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames| alternate splicing| and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle| whereas the encoded protein from the downstream ORF was found only in testis. In mouse| a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described| but the full-length sequence of only some were determined.

Research_area:Cell biology; Developmental biology; Signal transduction

Target_protein:DUSP13

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MDSP

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):20680

UniProt accession:Human: Q6B8I1; Mouse: Q6B8I0

Synonyms:MDSP

GeneID:Human: 51207; Mouse: 27389