MDM4 Monoclonal Antibody

SKU: BT-MCA3238

Size:100μL

Background:MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

Research_area:Cell Biology

Target_protein:MDM4

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:2D10F4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MDM4

Immunogen:Purified recombinant fragment of human MDM4 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):55kDa

UniProt accession:O15151

Synonyms:HDMX, MDMX, MRP1, MDM4

GeneID:4194