MCMBP Antibody - Cat. #: CSB-PA880100ESR2HU

SKU: CSB-PA880100ESR2HU

Size :50ul

Clone Number:

Aliases:MCMBP antibody; C10orf119 antibody; Mini-chromosome maintenance complex-binding protein antibody; MCM-BP antibody; MCM-binding protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BTE3

Immunogen:Recombinant Human Mini-chromosome maintenance complex-binding protein (1-240AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MCMBP

Research Areas:Epigenetics and Nuclear Signaling; Cell biology